Mary Margaret Ryan

Statistics Ph.D. Candidate at the University of California, Irvine
marymr [at] uci [dot] edu

Mary Ryan is a fifth-year Statistics Ph.D. candidate at the University of California, Irvine, working under Dr. Daniel Gillen. Her current research interests are in group sequential design and clinical trials, with applications in Alzheimer's Disease biomarker discovery. She is also a member of the Mizzou Mafia, graduating with the Class of 2016 from the University of Missouri, Columbia, with Bachelors in Journalism and Statistics.

Publications

Ryan, M.M., Cox, C.G., Witbracht, M., Hoang, D., Gillen, D.L., Grill, J.D. (2020). “Using Direct-to-Consumer Genetic Testing Results to Accelerate Alzheimer’s Disease Clinical Trial Recruitment.” (Accepted). Alzheimer Disease & Associated Disorders. d​oi.org/10.1097/wad.0000000000000421

Cox, C.G., Ryan, M.M., Gillen, D.L., Grill, J.D. (2020). “Is reluctance to share Alzheimer’s disease biomarker status with a study partner a barrier to preclinical trial recruitment?” The Journal of Prevention of Alzheimer's Disease. dx.doi.org/10.14283/jpad.2020.36 (opensouce link)

Ryan, M.M., Spotnitz, W.D., Gillen, D.L. (2020). “Variance estimation for the Kappa statistic in the presence of clustered data and heterogeneous observations.” Statistics in Medicine. doi.org/10.1002/sim.8522

Ryan, M.M., Grill, J.D., Gillen, D.L. (2019). “Participant and Study Partner Prediction and Identification of Cognitive Impairment in Preclinical Alzheimer's Disease: Study Partner vs. Participant Accuracy.” Alzheimer’s Research & Therapy. doi.org/10.1186/s13195-019-0539-3

Cox, C.G., Ryan, M.M., Gillen, D.L., Grill, J.D. (2019). “A preliminary study of clinical trial enrollment decisions among people with Mild Cognitive Impairment and their study partners.” The American Journal of Geriatric Psychiatry. doi.org/10.1016/j.jagp.2018.10.016

Posters, Presentations, & Short Courses

January 2021 | Variance estimation for the kappa statistic in the presence of clustered data and heterogeneous observations | Invited Presentation | ASA BIOP Webinar | UC Irvine

November 2020 | Variance estimation for the kappa statistic in the presence of clustered data and heterogeneous observations | Invited Presentation | Orange County Biostatistics Symposium | UC Irvine

November 2020 | Perceptions of Amyloid Imaging Among Cognitively Normal Older Adults with Elevated and Not Elevated Amyloid | Poster | Clinical Trials on Alzheimer’s Disease | UC Irvine

December 2019 | Using Direct-to-Consumer Genetic Testing Results in Alzheimer’s Disease Clinical Trial Recruitment | Poster | Clinical Trials on Alzheimer’s Disease | UC Irvine

July 2019 | An Extension of Cohen's Kappa for Clustered Data and Group Sequential Testing | Speed Talk & Poster | Joint Statistical Meetings | UC Irvine

July 2019 | Participant and Study Partner Prediction and Identification of Cognitive Impairment in Preclinical Alzheimer's Disease: Study Partner vs. Participant Accuracy | Poster | Alzheimer's Association International Conference | UC Irvine

June 2019 | An Investigation of the Kappa Statistic Under Clustered Data and Group Sequential Testing, with an Application to Surgical Rating | Paper & Presentation | Western North American Region Annual Meeting | UC Irvine

March 2019 | R: Models for Clustered and Correlated Data, Building Graphics in R | Short Course | Computer-Assisted Reporting Conference | UC Irvine

March 2018 | Scientific Necessity of Study Partners in Preclinical Alzheimer’s Disease Trials | Poster | ReMIND Emerging Scientists Symposium | UC Irvine

March 2018 | R: Machine learning and data models | Shourt Course| Computer-Assisted Reporting Conference | UC Irvine

April 2016 | Bridging gaps: An in-depth analysis of racial and ethnic wage gaps across industries around the 2008 recession | Poster | the MU Undergraduate Research and Creative Achievements Forum | University of Missouri, Columbia

April 2015 | An Analysis of Suicide and Bullying in the United States Using a Non-Gaussian Multivariate Spatial Model | Poster | the National Conference on Undergraduate Research & MU Undergraduate Research and Creative Achievements Forum | University of Missouri, Columbia

Updated January 2021