Zhaoxia Yu, Ph.D.
Associate Professor

Department of Statistics
University of California
Irvine, CA 92697-1250



Curriculum Vitae


Research Interests

Statistical modeling. In particular, statistical genetics, imaging genetics, and bioinformatics


Current Teaching

Statistics 120C

Statistics 200C


Fall 2016

I will be teaching Multivariate Statistical Methods (STAT140/240, syllabus). Prerequisite: STAT120C or Math121A.

Math121A is strongly recommended.


Courses that I taught before: STAT8, STAT120ABC STAT120C, STAT240, STAT257, STAT262, STAT200ABC


Selected peer-reviewed articles

(a complete list can be found here)

o   Yu Z, Demetriou M, Gillen D. (2015) Genome-wide analysis of gene-gene and gene-environment interactions using closed-form Wald tests. Genetic Epidemiology, 39: 446-455. (software: GG_Wald)

o   Yu Z, Li CF, Mkhikian H, Zhou RW, Newton BL, Demetriou M. (2014) Family studies of Type 1 diabetes reveal additive and epistatic effects between MGAT1 and three other polymorphisms. Genes and Immunity, 15:218-223.

o   Yu Z, Gillen D, Li CF, Demetriou M. (2013) Incorporating parental information into family-based association tests. Biostatistics, 14: 556-572.supplementary material

o   Yu Z (2012). Family-based association tests using genotype data with uncertainty. Biostatistics, 13:228-240.

o   Shahbaba B, Shachaf CM, Yu Z. (2012) A pathway analysis method for genome-wide association studies. Statistics in Medicine, 31:988-1000.

o   Yu Z, Deng L. (2011) Pseudosibship methods in the case-parents design. Statistics in Medicine, 30:3236-3251.

o   Yu Z, Wang S (2011). Contrasting linkage-disequilibrium as a multi-locus family-based association test. Genetic Epidemiology, 35:487-498.

o   Yu Z (2011). Testing gene-gene interactions in the case-parents design. Human Heredity, 71:171-179.

o   Weng L, Macciardi F, Subramanian A, Guffanti G, Potkin SG, Yu Z, Xie X. (2011) SNP-based pathway enrichment analysis for genome-wide association studies. BMC Bioinformatics, 12:99.

o   Browning B, Yu Z. (2009). Simultaneous genotype calling and haplotype phasing improves genotype accuracy and reduces false positive associations for genome-wide association studies. American Journal of Human Genetics, 85:847-861.

o   Yu Z, Garner C, Ziogas A, Anton-Culver H, Schaid D. (2009). Genotype determination for polymorphisms in linkage disequilibrium. BMC Bioinformatics, 10:63.

o   Yu Z, Wang L, Hildebrandt MAT, Schaid D. (2008). Testing whether genetic variation explains correlation of quantitative measures of gene expression, and application to genetic network analysis. Statistics in Medicine, 27:3847 - 3867.

o   Yu Z, Schaid D. (2007). Methods to impute missing genotypes for population data. Human Genetics, 122:495-504.

o   Yu Z, Schaid D. (2007). Sequential haplotype scan methods for association analysis. Genetic Epidemiology, 31: 553-564.


My son and daughter.