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UCI-led study reveals communication among organs, tissues regulating body's energy
An international research team led by the University of California, Irvine has identified a system of communication networks that exists among organs and tissues that regulate metabolism. Findings from their study provide, for the first time, a detailed “atlas” illustrating how the body creates and uses energy, and how imbalances in the networks may impact overall health.
Published today in the journal Cell, the research reveals the highly coordinated, multi-tissue metabolism underlying the body’s circadian rhythms and examines how disruptions in these rhythms – such as those caused by high-fat diets – induce misalignment among the network clocks and can trigger inflammation, which has been linked to major diseases and can affect lifespan.
Distinguished Professor of Computer Science Pierre Baldi and two ICS grad students performed computational analyses for the study.
Read the full story at UCI News.